Quinolones: a class of antimicrobial agents
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چکیده
منابع مشابه
Effect of quinolones and other antimicrobial agents on cell-associated Legionella pneumophila.
We evaluated the in vitro susceptibility of Legionella pneumophila ATCC 33152 (serogroup I) to 13 antibiotics alone and in combination with rifampin (0.1 mg/liter) by three methods. Extracellular susceptibility was determined by MIC determinations and time kill curves in buffered yeast extract broth, while intracellular susceptibility was determined by peripheral human monocytes in RPMI 1640 cu...
متن کاملPhotodegradation of some quinolones used as antimicrobial therapeutics.
The photostability of the fluoroquinolones ciprofloxacin (CPX), ofloxacin (OFX), and fleroxacin (FLX) toward ultraviolet irradiation (UVA) and room light was investigated in dilute aqueous solutions. A series of photoproducts was observed by high-performance liquid chromatography (HPLC) for all three drugs. As little as 1 h of exposure to room light was enough for the formation of detectable am...
متن کاملAntimicrobial Agents
Use of substances with antimicrobial properties is known to have been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. More recently, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism for some bacteria and discussed the merits of controlling these interactions in medicine. ...
متن کاملAntimicrobial Agents
INTRODUCTION................................................................. 13 PRECLINICAL TESTING STAGES ................................................................. 13 Discovery of New Antibiotics ................................................................. 13 Establishment of SAR ................................................................. 15 Animal Models for Studying the P...
متن کاملAntimicrobial agents.
The pharmacokinetics of apalcillin and piperacillin, each administered intravenously as a single 2-g dose, were compared in 10 volunteers in a randomized study of crossover design using bioassay and high-pressure liquid chromatographic procedures. The concentrations of both penicillins in serum were determined over a period of 12 h and in urine over 24 h. Concentrations of apalcillin and pipera...
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ژورنال
عنوان ژورنال: Veterinární Medicína
سال: 2001
ISSN: 0375-8427,1805-9392
DOI: 10.17221/7883-vetmed